ER Actor Stanley Tucci 'Wished He Could Have Done More' for Late 1st Wife Who Died of Cancer

Stanley Tucci, who starred in the hit medical drama TV series "ER," opened up about his first wife Kate who passed away from cancer in 2009.

When asked about whom he most like to say sorry during an interview in 2016, Tucci replied, "My late wife – she died of cancer."

"We tried everything we could do to save her," the actor added. "I wish that I could have done more and that I could have been with her at the moment she passed away. "

He continued, "I couldn't be in that room, because I knew it would be so devastating that I wouldn't be able to take care of the kids after."

"You don't have to worry about preparing to play the role of a father when you have three children!"

Kate, a social worker, succumbed to breast cancer in April 2009. She and Tucci tied the knot in 1995 and shared three children. They also raised Kate's two children from her past union with actor Alexander R. Scott.

In 2002, Tucci left his family and had an affair with actress Edie Falco. However, the relationship ended, and he returned to his family.

In another interview in 2010, the award-winning actor, who made his film debut in 1985's "Prizzi's Honor," got candid about his experience as a parent.

In that interview, he was asked what the challenge of being a parent is in a movie.

"You don't have to worry about preparing to play the role of a father when you have three children! I've also raised two stepchildren," he explained. "So no, no preparation is necessary. I prepare all the time."

In 2011, Tucci became engaged to English literary agent Felicity Blunt. The couple got married in a civil ceremony in summer 2012.

They have two children — son Matteo Oliver and daughter Emilia Giovanna.