'Full House' Star Dave Coulier Reveals New Diagnosis After Beating Non-Hodgkin Lymphoma

Just months after celebrating a major health milestone, the beloved sitcom star found himself back in a doctor’s office — facing a discovery no one expected.

Dave Coulier, best known as Uncle Joey on "Full House," has revealed that he is facing cancer for a second time.

Shortly after being declared cancer-free, the 66-year-old actor shared heartbreaking news with "Today" co-host Craig Melvin: doctors had discovered a new and unrelated form of cancer during a routine scan.

Coulier had previously been diagnosed with non-Hodgkin lymphoma in late 2024, after noticing a swollen lymph node in his groin. Following chemotherapy, a scan in March 2025 showed no signs of cancer, and he believed the fight was over.

But a few months later, a PET scan revealed an unusual area at the base of Coulier's tongue. Doctors weren't immediately sure what it was, but the scan showed something concerning enough to warrant further testing.

At first, doctors thought it was nothing. The first biopsy came back clean. But then the area grew. A second, larger biopsy was done. This time, the results were different — P16-positive oropharyngeal squamous cell carcinoma, a type of tongue cancer caused by HPV, was found.

"To go through chemotherapy and feel that relief of 'whoah, it's gone,' and then to get a test that says, well now you've got another kind of cancer... it is a shock to the system," Coulier said.

Doctors confirmed that this new cancer is completely unrelated to his earlier lymphoma. What's more chilling — Coulier had no symptoms at all. The cancer was found purely by chance, thanks to a scan he almost didn't need.

According to the American Cancer Society, P16-positive oropharyngeal cancers linked to HPV-16 generally respond well to treatment and have high survival rates. "We found it early enough where it's very treatable. ... It's got a 90% curability rate," Coulier explained. He has already started radiation therapy.

Despite the back-to-back diagnoses, Coulier remains resilient and hopeful. He credits routine checkups for catching the second cancer early, and believes they may have saved his life.