Courteney Cox Once Opened up about Motherhood, Miscarriages & the MTHFR Gene Mutation

Bettina Dizon
May 10, 2019
03:20 A.M.
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Courteney Cox, 54, revealed her MTHFR gene mutation, which causes a handful of possible problems that may arise in her offspring, her journey through motherhood, and her longing for more children with Johnny McDaid.


In an interview with New Beauty, Courtney Cox got real and shared the struggles she faced upon discovering her MTHFR gene mutation, which causes mental and physical health problems, as well as how she dealt with it.

“I suffered miscarriages, my dad died of a rare cancer, and depression runs in my family, which made my doctor think I should get this gene checked out,” she explained. 

Her particular case forced her to change her lifestyle, including her diet and medications, which turned out to be a positive change in her life. The actress regularly injects herself with methylated B-12 to give her energy and aid her condition. 


Cox shares a 14-year-old daughter, Coco, with her ex-husband, David Arquette, sharing her techniques in raising a child which includes allowing self-expression in the form of make-up.

“I want to keep an open relationship with her. I care more about what she’s watching than what she’s putting on her face,” Cox revealed.

At the age of 53, Cox still hopes for another child, even considering carrying another woman’s egg with her current beau, Irish musician, Johnny McDaid. 

Often, celebrities choose to keep their struggles private, as opposed to Cox who shared her struggles with the whole world. The actress believes that her story can guide others who face similar situations.


“If I can share any light or give any wisdom to somebody, I would share anything I can,” Cox said. “In the end, I think that’s important.”

There exist different types of gene mutations which may pose a health hazard among women, including BRCA1 gene mutation which increases the risk of developing breast. 

A victim of the illness mentioned above, Stephanie Kelly, was able to recover by getting a preventive double mastectomy shortly after finding out the sad news. Although it was a tough decision, she knew it was one she had to make.